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Boster Bio
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Image Search Results
Journal: International Journal of Molecular Sciences
Article Title: The Role of IGL-2 Preservation Solution on Rat Livers during SCS and HOPE
doi: 10.3390/ijms232012615
Figure Lengend Snippet: Expression of apoptosis-related marker active caspase 3 and inflammation marker HMGB1 in the perfusate during reperfusion following 24 h of SCS and 2 h of HOPE. ( A ) We observe no significant difference in the caspase 3 levels at T0 and T120. ( B ) HMGB1 ( p < 0.01) is significantly less expressed in the IGL2 group after 2 h of reperfusion. n = 6/group. ** = p < 0.01.
Article Snippet: Quantification of syndecan-1 (E-EL-R0996, Elabscience, Houston, TX, USA), heparan sulphate proteoglycan (E-EL-R0491, Elabscience, Houston, TX, USA), high mobility group protein B1 (E-EL-R0505, Elabscience, Houston, TX, USA), and
Techniques: Expressing, Marker
Journal: International Journal of Molecular Sciences
Article Title: The Role of IGL-2 Preservation Solution on Rat Livers during SCS and HOPE
doi: 10.3390/ijms232012615
Figure Lengend Snippet: Expression of apoptosis-related marker active caspase 3 and inflammation marker HMGB1 in the perfusate during reperfusion following 24 h of SCS and 2 h of HOPE. Caspase 3 ( p = 0.02) and HMGB1 ( p = 0.03) were significantly less expressed in the IGL2 group after 2 h of reperfusion. n = 6/group. * = p < 0.05.
Article Snippet: Quantification of syndecan-1 (E-EL-R0996, Elabscience, Houston, TX, USA), heparan sulphate proteoglycan (E-EL-R0491, Elabscience, Houston, TX, USA), high mobility group protein B1 (E-EL-R0505, Elabscience, Houston, TX, USA), and
Techniques: Expressing, Marker
Journal: Science Advances
Article Title: KRAS G12V /HLA-A*02:01–targeted chimeric antigen receptor T cells exhibit potent preclinical activity against solid tumors
doi: 10.1126/sciadv.aea2511
Figure Lengend Snippet: ( A ) Histomorphological validation of PDOs. Top: Hematoxylin and eosin (H&E) staining of primary tumor tissues from three independent patients with CRC (scale bars, 50 μm). Middle: Bright-field images of the matched PDOs (scale bars, 100 μm). Bottom: H&E staining of PDOs showing maintained tumor architecture (scale bars, 50 μm). ( B ) Caspase-3 (c-cas3)–dependent apoptosis in organoids after 24 hours of coculture with CAR T cells at a 1:1 E:T ratio was quantified by cleaved caspase-3 ELISA ( n = 3 biological replicates). ** P < 0.01. ( C ) Levels of TNF-α (left) and IFN-γ (right) released by CD19 CAR T cells and B9 CAR T cells in the culture supernatant of coculture with PDOs after 24 hours at a 1:1 E:T ratio ( n = 3 biological replicates). Data are represented as the means ± SD. Significance determined by two-way ANOVA with Tukey’s post hoc test: *** P < 0.001.
Article Snippet: Supernatants collected after 24 hours were analyzed for cytokines, while apoptosis was determined by
Techniques: Biomarker Discovery, Staining, Enzyme-linked Immunosorbent Assay